ALD-52 powder (1-acetyl-LSD) is a lysergamide derivative and chemical analogue of lysergic acid diethylamide (LSD), first synthesized in the 1950s. This research chemical functions as a prodrug, converting to LSD in vivo and producing psychedelic effects comparable to those of its parent compound.
With a molecular formula of C22H27N3O2 and a molecular weight of 365.47 g/mol, this powder exhibits high purity (>98%) and is intended exclusively for research and forensic applications. The compound demonstrates affinity for serotonin receptors 5-HT1A, 5-HT2A, and 5-HT2C, with binding affinities of 1054, 174, and 10.2 nM, respectively, and elicits head-twitch response (HTR) in vivo studies. Storage at -20°C in powder form ensures stability for up to 3 years.
Important Research Considerations
This substance is classified as a psychedelic and is subject to controlled substance regulations in many jurisdictions. Under the US Federal Analog Act, it is treated as an analogue of LSD, and in the UK, it is specifically named as a Class A drug. The compound is not approved for human consumption and is strictly limited to research purposes.




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